Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.

Tumor necrosis factor- α, adiponectin and their ratio in gestational diabetes mellitus

Background: It has been suggested that inflammation might be implicated in the gestational diabetes mellitus (GDM) complications, including insulin resistance. The aims of the current study were to explore maternal circulating values of TNF-α, adiponectin and the adiponectin/TNF-α ratio in women with GDM compared with normal pregnancy and their relationships with metabolic syndrome ...

New Insight into the Relation between Adiponectin and Diabetes

Diabetes mellitus is a group of metabolic diseases. Insulin resistance is defined as a state that needs more insulin to get the biological effects achieved by a lower amount of insulin in the normal state. Several molecules which are secreted through adipocytes have been involved in insulin resistance and type 2 diabetes mellitus. Adiponectin as a 244 amino acid protein is exclusively expressed...

Serum Adiponectin Level and Clinical, Metabolic, and Hormonal Markers in Patients with Polycystic Ovary Syndrome

Association of adiponectin gene rs2241766 polymorphism with serum adiponectin level, Insulin resistance and type 2 diabetes mellitus in an Iranian population

Introdution: Adiponectin is a peptide secreted from fat cells that plays an important role in the development of insulin resistance and type 2 diabetes. A number of single nucleotide polymorphisms in the adiponectin gene are associated with lower adiponectin expression and T2DM. The aim of this study was to determination the frequency of rs 2241766 polymorphism in adiponectin gene and its relat...

Soy Isoflavone Genistein Is a Potential Agent for Metabolic Syndrome Treatment: A Narrative Review

Metabolic syndrome has a high prevalence (about 22.4% in adult individuals) in developed countries. Inflammation due to obesity and fat accumulation is the most important factor in the progression of metabolic syndrome. In cells which have a receptor for insulin hormone, inflammatory mediators target the insulin signaling pathway and cause insulin resistance. Peroxisome proliferator-activated r...